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Observational study on the effect of Helicobacter pylori infection eradication treatment on the gastrointestinal flora

Observational study on the effect of Helicobacter pylori infection eradication treatment on the gastrointestinal flora

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073419
Enrollment
Unknown
Registered
2023-07-11
Start date
2023-07-11
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter infection

Interventions

Tailored treatment Group(Clarithromycin):N/A
Classic Bismuth Quadruple Treatment Group:N/A
Dual Thrapy Group:N/A
Tailored treatment Group(Levofloxacin):N/A

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: Patients who visited our hospital for gastroscopy and colonoscopy 2: Positive UBT and gastroscopic mucosal biopsy suggesting positive Hp RUT 3: No previous treatment for Hp infection eradication 4: Age = 18 years 5: Voluntary participation and ability to cooperate with the study

Exclusion criteria

Exclusion criteria: 1: Drugs that may affect the study results, such as PPI, P-CAB, H2 receptor blockers, bismuth, antibiotics, etc., had been taken within four weeks before enrollment 2: Patients with gastrointestinal malignancies 3: Patients with gastrinoma 4: Patients with postoperative gastrointestinal or esophageal surgery 5: Patients with serious heart, lung, kidney, liver, hematological, neurological, endocrine, and psychiatric system diseases 6: Patients who are allergic to the drugs used in this study 7: Pregnant or breastfeeding women who have not planned to have a pregnancy in the past 1 year 8: Combination of other medical conditions that may increase the side effects of treatment 9: Patients who cannot give informed consent or cannot cooperate with the study

Design outcomes

Primary

MeasureTime frame
ß-Diversity;a-Diversity;

Secondary

MeasureTime frame
Compliance;Eradication rate;Safety (incidence of adverse reactions);

Countries

China

Contacts

Public ContactZhiqiang Song

Department of Gastroenterology, Peking University Third Hospital

18910192576@163.com+86 189 1019 2576

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026