Infant diet and gut microbiota maturation and growth development associations (Study of their regularity)
Conditions
Interventions
Observation group:None
Sponsors
Gynecology and Obstetrics Hospital Affiliated to Jiangnan University (Wuxi maternal and child health care)
Eligibility
Sex/Gender
All
Age
1 Months to 3 Months
Inclusion criteria
Inclusion criteria: (1) Singleton healthy full-term normal births. (2) The mother or infant is in good health. (3) Local permanent residents and family members with no communication barriers. (4) Voluntary compliance and cooperation with the questionnaire and follow-up sampling and follow-up requirements.
Exclusion criteria
Exclusion criteria: (1) Assisted reproduction. (2) Twins and above. (3) The mother has a chronic/infectious/major disease of her own, or hypertension, diabetes, etc. during pregnancy. (4) Mother has received antibiotics for more than 7 days during the perinatal period or lactation, or the infant has received antibiotics for more than 7 days after birth. (5) The mother is taking probiotic/prebiotic dietary supplements for a long time during the perinatal period or lactation, or the infant is taking probiotic/prebiotic dietary supplements for a long time after birth. (6) The mother or infant is participating in a nutritional or pharmacological intervention study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition intestinal microflora;Fecal metabolomics;Fecal immunoomics;Urine metabolomics;Breast milk flora;Breast milk nutrients;Blood metabolomics;Blood immunoomics;Infant diet;Physical health of infants (Routine and regular medical check-ups);Immune development level of infants; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological development of infants;Nutrition during pregnancy;Nutrition during lactation;Children's cognitive behavior;Children's bone dens; | — |
Countries
China
Contacts
Public ContactHeng Zhang
Gynecology and Obstetrics Hospital Affiliated to Jiangnan University (Wuxi maternal and child health care)
Outcome results
None listed