Frailty
Conditions
Interventions
Gold Standard:frailty phenotype score
Index test:Bedside muscle ultrasound
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Surgical treatment of gastric or colorectal cancer under general anesthesia by endotracheal intubation; 2. Aged greater than or equal to 65 years, male or female; 3. ASA grade I-IV level; 4. Join voluntarily and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from muscle-related diseases such as myasthenia gravis, inflammatory myopathy and progressive muscular dystrophy; 2. Suffering from diseases such as Parkinson's disease, fracture, paraplegia, amputation, sequela of cerebral infarction and so on; 3. At the end stage of chronic disease; 4. Taking drugs that have been shown to cause symptoms similar to weakness, including Donepezil Hydrochloride, L-dopa and antidepressants; 5. Those who are unable to cooperate with severe dementia, disturbance of consciousness or cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under Receiver Operating Characteristic Curve (ROC) of Cross-sectional area of rectus femoris;Area under ROC curve of circumference of rectus femoris;Area under ROC curve of rectus femoris thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitivity;Specificity;Positive predictive value;Negative predictive value;Yoden index;Cross-sectional area of rectus femoris;Thickness of rectus femoris;Circumference of rectus femoris;frailty phenotype score;Clinical frailty scale;Surgical Apgar score;Postoperative complication;Clavien-Dindo rating;Postoperative ICU stay time;Postoperative hospital stay;Transfer after discharge from hospital;Postoperative 30-day mortality;Re-admission within 30 days after operation;age;hemodynamic parameters;Surgery and Duration of Anesthesia;blood pressure;temperature;blood sugar;Body Mass Index;American Society of Anesthesiologists grade;liquid intake and output volume;blood gas analysis;Anesthetic analgesics;Sedative;Skeletal muscle relaxants;Vasoactive drug;Body surface area;Basic diseases;The grip strength drops;Slow down the pace;Weight loss;feeling tired;low physical activity;the International Physical Activity Questionnaire-short term, IPAD-s; | — |
Countries
China
Contacts
Public ContactYue Liu
Nanjing Drum Tower Hospital
Outcome results
None listed