Skip to content

To investigate the gut microbiota-dependent mechanism of POCD in patients with gastrectomy under general anesthesia at different time

To investigate the gut microbiota-dependent mechanism of POCD in patients with gastrectomy under general anesthesia at different time

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073403
Enrollment
Unknown
Registered
2023-07-10
Start date
2022-09-21
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

am anesthesia group:N/A
pm anesthesia group:N/A

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Gender is not limited; (2) Age = 18 years old; (3) ASA classification I-III; (4) Inpatients requiring gastrectomy; (5) Possess basic reading and comprehension skills, or have clear questions and answers, and can complete the scale survey with the help of medical staff. (6) Those who signed the informed consent, voluntarily participated in the project and were able to complete the questionnaire survey and related monitoring as required.

Exclusion criteria

Exclusion criteria: (1) Patients with anxiety, depression and other mental diseases and other neurological diseases; (2) Patients with cognitive impairment; (3) Patients with severe heart, lung, liver, kidney, brain, digestive tract and other serious diseases, and the researchers believe that patients are not suitable to participate in this study; (4) Patients with drug addiction, alcohol abuse or mental disorders, unable to cooperate or insist on treatment, and poor compliance; (5) Patients with severe sleep disorders; (6) The patient is participating in other clinical trials at the same time; (7) Any person who is considered inappropriate by the investigator to participate in this trial for other reasons.

Design outcomes

Primary

MeasureTime frame
gut microbia;Cognitive Function Assessment;

Secondary

MeasureTime frame
Serum metabolite;

Countries

China

Contacts

Public ContactZhou Huixuan

The First Affiliated Hospital of Nanjing Medical University

wenzhu123.zhou@163.com+86 139 1388 4657

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026