Efficacy and safety of long-term prone ventilation in patients with critically ill COVID-19 pneumonia: a single-center, prospective, randomized controlled study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073402

Enrollment

Unknown

Registered

2023-07-10

Start date

2023-07-10

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with critically ill Covid-19 pneumonia

Interventions

Long duration prone position:The patients were treated with prolonged prone ventilation for more than 24 hours

Standard prone position ventilation was used for treatment:Standard prone position ventilation was used for treatment

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of the tenth edition of the diagnosis and treatment protocol "critical COVID-19"; (2) Age 18-85 years old; (3) Patients undergoing mechanical ventilation;

Exclusion criteria

Exclusion criteria: (1) severe intra-abdominal pressure increase (2) intracranial pressure increase (3) Recent history of facial, chest and abdominal, fracture, spine and other operations; (4) Confirmed venous thromboembolism, and anticoagulation treatment less than 2 days; (5) Hemodynamic instability; (6) pregnancy status; (7) Research objects deemed unsuitable by researchers.

Design outcomes

Primary

Measure	Time frame
Oxygenation index;	—

Secondary

Measure	Time frame
Static lung compliance of the respiratory system;	—

Countries

China

Contacts

Public ContactYinchuan Li

Shanghai 10th People's Hospital

yingchuan.li@sjtu.edu.cn+86 136 8194 5425

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026