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Comparison of the clinical outcomes in PCOS patients with letrozole resistance undergoing ovulation induction using letrozole "stair-step"protocol versus traditional gonadotropin protocol

Clinical efficacy evaluation of letrozole incremental regimen in patients with polycystic ovary syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073384
Enrollment
Unknown
Registered
2023-07-10
Start date
2023-07-10
Completion date
Unknown
Last updated
2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovarian syndrome

Interventions

study group:letrozole
control group:Gn protocol

Sponsors

Shanghai First Maternity and Infant Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: aged younger than 40 years old;PCOS patients with letrozole resistance

Exclusion criteria

Exclusion criteria: Severe liver or kidney diseases; severe systemic diseases; receipt of hormone treatments within the previous 3-month period; participation in any other clinical trial in 3 months.

Design outcomes

Primary

MeasureTime frame
Multifollicular development rate;

Secondary

MeasureTime frame
monofollicular development rate; ovulation rate;cancellation rate;OHSS ;clinical pregnancy rate;

Countries

China

Contacts

Public ContactZhu Xiuxian

Shanghai First Maternity and Infant Hospital

zhuxiuxian@163.com+86 188 1782 1575

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026