knee osteoarthritis (KOA)
Conditions
Interventions
4-week acupuncture group :Electro-acupuncture will be administered 3 times a week for a total of 4 weeks
8-week acupuncture group :Electro-acupuncture will be administered 3 times a week for a total of 8 weeks
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 45-75 years (both genders) 2. Diagnosed with KOA according to the ACR criteria 3. Unilateral/bilateral chronic knee pain for over 3 month 4. Radiologic confirmation of KOA within 6 months Kellgren-Lawrence (KL) grade II or III 5. The average score for knee pain during walking on flat ground was 4 or more out of 10 on a numerical rating scale (NRS) in the last week 6. Written informed consent
Exclusion criteria
Exclusion criteria: 1. History of knee surgery or waiting for surgery (knee replacement or arthroscopic knee surgery) 2. Knee pain caused by other diseases (autoimmune diseases, infection, malignant tumours, trauma, fracture, joint loose bodies, severe effusion of joint cavity, lumbosacral vertebrae disease, gout, etc.) 3. Arthroscopy within 1 year and intra-articular injection in the past 6 months 4. Acupuncture treatment during the past 6 months 5. Serious acute or chronic organ diseases or mental disorders 6. Blood coagulation disorders 7. Pregnancy and breastfeeding 8. Cardiac pacemaker and epilepsy 9. Participation in another clinical study within 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Response rates at weeks 4, 8 and 16;WOMAC pain subscale;WOMAC function subscale ;WOAMC stiffness subscale;SF-12;Patient global assessment ;The Osteoarthritis Research Society International (OARSI) response rate ;Rescue medicine ;NRS; | — |
Countries
China
Contacts
Public ContactCun-Zhi Liu
Beijing University of Chinese Medicine
Outcome results
None listed