The role and mechanism of peroxidase reductase 6 in pulmonary injury associated with mechanical ventilation

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073376

Enrollment

Unknown

Registered

2023-07-09

Start date

2023-07-06

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical ventilator-related lung injury

Interventions

Group of mechanical ventilator-related lung injury:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-65 years who require prolonged mechanical ventilation (> 3 hours) for various reasons and who are excluded from lung and other organ or tissue infections through clinical manifestations, pulmonary auscultation, imaging and blood routine examination are eligible for inclusion.

Exclusion criteria

Exclusion criteria: Patients with a history of smoking, systemic inflammatory disease, or various reasons that preclude bronchoscopy and alveolar lavage.

Design outcomes

Primary

Measure	Time frame
PRDX6 protein level and TNF-aIL-1ßIL-6 level in BALF ;PRDX6 protein level and TNF-aIL-1ßIL-6 level in blood;	—

Countries

China

Contacts

Public ContactShen Qiying

The First Affiliated Hospital of Anhui Medical University

shenqiying-yy@163.com+86 139 5602 9032

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026