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The diagnostic performance of contrast-enhanced ultrasonography with sonazoid in differentiating benign and malignant cervical lymph nodes: a perspective single-center research

The diagnostic performance of contrast-enhanced ultrasonography with sonazoid in differentiating benign and malignant cervical lymph nodes: a perspective single-center research

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073362
Enrollment
Unknown
Registered
2023-07-07
Start date
2020-10-13
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical lymph node metastasis

Interventions

Gold Standard:cytology and postoperative histology results
Index test:The diagnosis results of contrast-enhanced ultrasonography with Sonazoid

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adults aged >= 18 years with cancer; 2. Have not received surgical or chemical treatment or radiotherapy before; 3. One or more imaging methods indicate suspected cervical lymph node metastasis indicated cervical lymph nodes suspected for metastasis; 4. Underwent fine-needle aspiration cytology and thyroglobulin (Tg) measurement in washout fluid from biopsy (FNA-Tg) examinations or intraoperative quick-frozen pathological examination within a week after the US and CEUS examinations.

Exclusion criteria

Exclusion criteria: 1. Patients who were allergic to eggs and were not suitable for CEUS examinations; 2. Had an angina attack in the last six months or have had prior severe coronary artery disease; 3. Had severe lung diseases; 4. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
The diagnosis of contrast-enhanced ultrasonography with Sonazoid;specificity;negative predictive value;positive predictive value;

Secondary

MeasureTime frame
Sographicfeatures of contrast-enhanced ultrasonography with Sonazoid;Sensitivity;

Countries

China

Contacts

Public ContactZhou Jianhua

Sun Yat-Sen University Cancer Center

zhoujh@sysucc.org.cn+86 137 1175 7623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 19, 2026