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Effect of intravenous lidocaine infusion on rebound pain after brachial plexus block

Effect of intravenous lidocaine infusion on rebound pain after brachial plexus block

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073339
Enrollment
Unknown
Registered
2023-07-07
Start date
2023-07-10
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of upper limb

Interventions

Intravenous lidocaine group (Group L):After successful block, 100mg lidocaine was diluted to 100ml with normal saline for about 30min through intravenous infusion.
Normal saline group (Group C):After successful block, 100ml normal saline was injected intravenously for about 30min.

Sponsors

904th Hospital of the Joint Logistic Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral upper limb fractures undergoing elective brachial plexus block anesthesia with open reduction and internal fixation were of all genders, aged 18-80 years, BMI 18-30kg /m², ASA grade I or II.

Exclusion criteria

Exclusion criteria: Patients with multiple injuries with abnormal coagulation function, puncture site infection, allergy to local anesthetics or general anesthetics, and other operations, preoperative neurological damage, cognitive dysfunction, or mental system diseases, were unable to cooperate, and the researchers considered it inappropriate to be included in the study.

Design outcomes

Primary

MeasureTime frame
Occurrence of rebound pain within 48 h of block administration;Duration of rebound pain within 48 h of block administration;

Secondary

MeasureTime frame
Sensory block time within 48 h of administration;Movement block time within 48 h of administration;Drug dosage of analgesic pump for 48 h blocked administration;VAS pain scores at rest and activity before surgery and 8, 12, 24, and 48h after nerve block administration;Sleep quality on the night of surgery: Athens Insomnia Scale;MMSE scores were recorded 1 day before surgery and 1 day and 3 days after surgery to evaluate the occurrence of POCD.;

Countries

China

Contacts

Public ContactLi Jiaying

904th Hospital of the Joint Logistic Support Force

1875447326@qq.com+86 132 1857 7211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026