Skip to content

Effect of colloid preload combined with crystal co-load and colloid and crystal co-load on blood pressure and cardiac output of women under spinal anesthesia under combined prophylactic noadrenaline infusion

Effect of colloid preload combined with crystal co-load and colloid and crystal co-load on blood pressure and cardiac output of women under spinal anesthesia under combined prophylactic noadrenaline infusion

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073333
Enrollment
Unknown
Registered
2023-07-07
Start date
2023-07-10
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after spinal anesthesia

Interventions

Colloid preload group:500mL of 6% hydroxyethyl starch 130/0.4 was received 20 minutes before the start of spinal anesthesia, and 500mL of Ringer's fluid was pressurized immediately after intrathecal i
Co-load group:Pressure infusion of 500mL 6% hydroxyethyl starch 130/0.4 and 500ml Ringer's fluid was initiated immediately after intrathecal injection.

Sponsors

Fujian Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Condition Grade II, with a term pregnancy scheduled for cesarean delivery under spinal anesthesia

Exclusion criteria

Exclusion criteria: age under 19 years or over 40 years; Height less than 150 cm, weight less than 60 kg, BMI greater than or equal to 40kg/ m2; The presence of any contraindications to spinal anesthesia (increased intracranial pressure, coagulation dysfunction, or skin infection at the puncture site); Chronic or pregnancy-induced hypertension; Baseline systolic blood pressure (BP) greater than 140 mm Hg; Hemoglobin less than 10 g/dL; Diabetes, cardiovascular, cerebrovascular or kidney disease; Hyperamniotic fluid or known fetal malformation, multiple births, emergency.

Design outcomes

Primary

MeasureTime frame
blood pressure;cardiac output;Blood gas analysis of umbilical cord blood;cardiac index;

Secondary

MeasureTime frame
stroke volume;heart rate;

Countries

China

Contacts

Public ContactXiang Gao

Department of Anesthesiology, Fujian Maternal and Child Health Hospital

xianggao_fmu@163.com+86 130 0388 1531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026