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The effect of corneal nerve recovery and tear neuromediator change on corneal epithelium remodeling after SMILE

The effect of corneal nerve recovery and tear neuromediator change on corneal epithelium remodeling after SMILE

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073317
Enrollment
Unknown
Registered
2023-07-06
Start date
2023-04-10
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive errors

Interventions

Moderate myopia (SMILE surgery):None
low myopia (SMILE surgery):None

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-50 years old; 2. Stable refractive state for at least 2 years; 3. Stop wearing soft corneal contact lenses for more than one week; 4.The degree of spherical lens is <=-6.00D, the degree of cylindrical lens is <=-2.00D; 5. Corrected visual acuity = 0.8.

Exclusion criteria

Exclusion criteria: Patients with intraoperative and postoperative complications; Patients who are unable to follow up on time.

Design outcomes

Primary

MeasureTime frame
Corneal epithelial thickness;

Secondary

MeasureTime frame
Corneal nerve;Morphology of corneal epithelial cells;

Countries

China

Contacts

Public ContactZhaoShaozhen

Tianjin Medical University Eye Hospital

zhaosz1997@sina.com+86 138 0203 6813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026