lung cancer
Conditions
Interventions
Group 1:Sublobectomy
Group 2:lobectomy
Sponsors
Shengjing Hospital Affiliated to China Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) 1. Enhanced computed tomography (CT) or thin-slice chest CT found isolated lung malignancies less than or equal to 2cm; (2) No suspicious lymph node involvement; (3) between 20 and 60 years old; (4) Preoperative lung function was normal, male FEV1=2500ml, female FEV1=1800ml, FEV1/FVC > 80%; (5) Preoperative blood gas analysis of arterial oxygen partial pressure > 65 torr; (6) Surgical pathology confirmed non-small cell lung cancer, no malignant pleural effusion or pleural spread, no lymph node involvement; (7) Technically feasible lobectomy, segmental resection, wedge resection and lymph node dissection; (8) Obtain the patient's written informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) multiple lung cancers; (2) Tumor history; (3) History of hormone therapy; (4) Have taken aspirin within a week; (5) receiving medication; (6) Cardiovascular and cerebrovascular diseases, endocrine system diseases, immune system diseases; (7) The patient had a history of thoracic surgery; (8) Active bacterial or fungal infection (9) Pregnant or lactating women; (10) interstitial pneumonia, pulmonary fibrosis or severe emphysema; (11) Suffering from mental illness and unable to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local recurrence rate;recurrence free survival ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative respiratory function;Overall survival;adverse event;Completion ratio of pulmonary segment resection and lobectomy; | — |
Countries
China
Contacts
Public ContactZhang Suning
Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
Outcome results
None listed