Demand for postoperative analgesic drugs in patients undergoing gynecological laparoscopic surgery
Conditions
Interventions
Test group E1:Low dose of esketamine
Test group E2:High dose of esketamine
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? In line with the surgical indications, gynecologic laparoscopic surgery is planned; ? ASA grade I and II; ? Age: 18-65 years old; ? Patients gave informed consent to this study.
Exclusion criteria
Exclusion criteria: ? Those who received immunosuppressive treatment 3 months before enrollment, and those with blood, circulatory system or immune system diseases; ? Preoperative opioid use, body mass index (BMI) > 35; ? Major organ dysfunction; ? Pregnant and lactating women; ? Allergic to the drugs used in this study. ? Those who are unwilling or unable to use patient-controlled analgesia (PCA) devices, and those who are unable to use the pain digital Rating Scale (NRS).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dosage of analgesic drugs used by PCIA within 24 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting pain NRS score;Opioid dosage;Remedial analgesic drug dose;Sedation score;Opioid related adverse reactions;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactJuying Jin
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed