Application of prophylactic inhalation of penehyclidine hydrochloride to improve pulmonary complications in patients with chronic bronchitis after surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073265

Enrollment

Unknown

Registered

2023-07-05

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary complications

Interventions

Group of chronic bronchitis:Penehyclidine hydrochloride atomized inhalation

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? The patient had a clear diagnosis of chronic bronchitis but no acute pulmonary infection; ? Operation time > 2 hours; ?ASA Grade II-III

Exclusion criteria

Exclusion criteria: ? Patients who are unable to cooperate in inhalation therapy; ? Moderate to severe symptomatic prostatic hypertrophy or narrow-angle glaucoma; Inhaled beta-2 agonists, muscarinic antagonists, and/or glucocorticoids within 1 month before surgery; Myocardial infarction, severe cardiac dysfunction (New York Heart Association rating higher than level 3), or tachyarrhythmia that occurred within 1 year; (5) Need kidney replacement therapy; ? Severe liver dysfunction (Child-PughC class); ? Participate in other drug trials within 1 month before surgery

Design outcomes

Primary

Measure	Time frame
None;	—

Countries

China

Contacts

Public ContactWANG ZHAO

The Second Affiliated Hospital of Zunyi Medical University

zy2ane@126.com+86 139 8428 2588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026