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The relationship between oral and Gut microbiota and the progression of brain glioma and its clinical value

The relationship between oral and Gut microbiota and the progression of brain glioma and its clinical value

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073255
Enrollment
Unknown
Registered
2023-07-05
Start date
2023-06-30
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain glioma

Interventions

Disease Group:None
Healthy Control Group:None

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria of Disease Group: (1) the patients were diagnosed with glioma by pathological diagnosis and imaging analysis; (2) Participant aged>18 years old; (3) All participants were not undergoing antibiotics treatment within 2 months before the specimens were collected. Inclusion Criteria of Healthy Control Group: (1) The participants were recruited from glioma patients' families;(2) Participant aged>18 years old; (3) All participants were not undergoing antibiotics treatment within 2 months before the specimens were collected.

Exclusion criteria

Exclusion criteria: 1. All participants were in pregnancy and lactation; 2. The patients were in a severe unconscious state; 3. The subjects had a history of liver and kidney dysfunction; 4. The subjects had a history of malignant tumors in other parts of body; 5. The subjects with severe infections and must use broad-spectrum antibiotics.

Design outcomes

Primary

MeasureTime frame
Diversity and difference and metabolimics of intestinal microbiota in paticipants ;Diversity and difference and metabolimics of oral microbiota in paticipants;Diversity and difference and metobolimics of glioma brain tissue microbiota in paticipants;

Countries

China

Contacts

Public ContactLi Zhiqiang

Zhongnan Hospital of Wuhan University

Lizhiqiang@whu.edu.cn+86 189 0712 3005

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026