brain glioma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria of Disease Group: (1) the patients were diagnosed with glioma by pathological diagnosis and imaging analysis; (2) Participant aged>18 years old; (3) All participants were not undergoing antibiotics treatment within 2 months before the specimens were collected. Inclusion Criteria of Healthy Control Group: (1) The participants were recruited from glioma patients' families;(2) Participant aged>18 years old; (3) All participants were not undergoing antibiotics treatment within 2 months before the specimens were collected.
Exclusion criteria
Exclusion criteria: 1. All participants were in pregnancy and lactation; 2. The patients were in a severe unconscious state; 3. The subjects had a history of liver and kidney dysfunction; 4. The subjects had a history of malignant tumors in other parts of body; 5. The subjects with severe infections and must use broad-spectrum antibiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diversity and difference and metabolimics of intestinal microbiota in paticipants ;Diversity and difference and metabolimics of oral microbiota in paticipants;Diversity and difference and metobolimics of glioma brain tissue microbiota in paticipants; | — |
Countries
China
Contacts
Zhongnan Hospital of Wuhan University