chronic kidney disease
Conditions
Interventions
Experimental group:Jingtian particles
Control group:placebo
Sponsors
Hubei Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Age of 18-75 years old; ? Meet the diagnostic criteria of chronic kidney disease stage 3-5: eGFR < 60 mL/(min*1.73 m2), and is a relatively stable non-dialysis stage; ? Conforming to the TCM diagnostic criteria of deficiency of both qi and Yin and stagnation of water turbidity; ? stable blood pressure below 140/90 mmHg after basic treatment; ?24 h urinary protein = 2.0 g/24 h;
Exclusion criteria
Exclusion criteria: ? Receiving dialysis or hormone, non-steroidal anti-inflammatory drugs, immunosuppressive therapy; ? Severe arrhythmia, acute heart failure, myocardial infarction, acute stroke, unstable angina, NYHA class ? (New York Heart Association classification standard); ? patients with acute infectious diseases, active malignant tumors, active and prolonged chronic hepatitis B, decompensated liver cirrhosis, severe primary diseases such as hematopoietic system, active tuberculosis or mental illness; ? eGFR fluctuation = 30% within 3 months before enrollment; ? serum potassium higher than the upper limit of the reference interval; ? known to be allergic or intolerant to one of the drugs in the study; ? Pregnant or lactating patients; ? Patients who are participating in other clinical studies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatinine;Glomerular filtration rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour urinary protein quantification; | — |
Countries
China
Contacts
Public ContactBa Yuanming
Hubei Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed