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Clinical and mechanism study of Xuanfei Jingshui decoction in the treatment of IgA nephropathy based on intestinal flora

Clinical and mechanism study of Xuanfei Jingshui decoction in the treatment of IgA nephropathy based on intestinal flora

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073242
Enrollment
Unknown
Registered
2023-07-05
Start date
2023-07-05
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy

Interventions

Traditional Chinese Medicine Treat Group:Xuanfei Jing Shui decoction + basic treatment
Control group:Basic treatment

Sponsors

Changzhou Hospital of traditional Chinese Medicine Affiliated to Nanjing University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age of 18-70 years old, regardless of gender; 2. IgAN was diagnosed by renal biopsy 3.e-GFR=30mL /min(CKD-EPI formula); 4. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of other renal diseases not caused by IgAN; 2. Patients who have received formal IgAN-related treatment; 3.Patients with unstable angina pectoris, myocardial infarction and coronary stent implantation within 3 months; 4. History of hepatic failure and/or hepatic encephalopathy; 5. Patients with malignant tumors or malignant diseases affecting the overall prognosis; 6. Pregnant and lactating women; 7. History of unilateral or bilateral renal artery stenosis; 8. Alcoholics or drug users; 9. Is participating in another clinical investigation.

Design outcomes

Primary

MeasureTime frame
Urine protein;

Secondary

MeasureTime frame
Urinary Red Cell Count;Urinary ß2 microglobulin;Urinary transferrin;Routine urine test;Blood serum creatinine;Blood urea nitrogen;Cystatin C;Blood uric acid;Estimate the glomerular filtration rate;Blood lipids;Complement C3;Immunoglobulin A;Body mass index;intestinal flora;

Countries

China

Contacts

Public ContactChenghua Zhang

Changzhou Hospital of traditional Chinese Medicine Affiliated to Nanjing University of traditional Chinese Medicine

zch19940323@163.com+86 150 6255 8263

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026