periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Age 18-65 years; ? Diagnosed as stage III or IV extensive periodontitis according to the 2018 consensus classification of periodontal and peri-implant diseases and conditions; ? Good compliance and good oral hygiene practices; able to obtain informed consent.
Exclusion criteria
Exclusion criteria: ? Smoking (>10 cigarettes/day); ? Women who are pregnant or breastfeeding; ? Those with systemic diseases such as oncology, diabetes, cardiovascular disease, etc; ? Those who have received periodontal treatment in the past 6 months; ? Those who have taken medication affecting periodontal status such as antibiotics, immunosuppressants and glucocorticoids in the past 6 months; ? Those who, in the opinion of the investigator, are otherwise unsuitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical attachment loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| probing depth;keratinized tissue width;bleeding index;alveolar bone height; | — |
Countries
China
Contacts
Shanghai Stomatological Hospital