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A study on the efficacy and safety of hybrid electroconvulsive therapy in patients with manic phase of bipolar disorder

A study on the efficacy and safety of hybrid electroconvulsive therapy in patients with manic phase of bipolar disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073236
Enrollment
Unknown
Registered
2023-07-05
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Manic episodes of bipolar disorder

Interventions

ECT Group:Standard Electroconvulsive therapy (ECT)
HECT Group:Hybrid-ECT

Sponsors

The Second People's Hospital of Huizhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) 18 years old < Age < 60 years old, 2) hospitalized patients with bipolar disorder diagnosed according to ICD-10 and current manic episode, with or without psychotic symptoms; 3) Young Mania Scale (YMRS) =20; 4) Informed consent can be signed.

Exclusion criteria

Exclusion criteria: 1) pregnancy; 2) participated in other relevant investigators within 30 days before enrollment; 3) received ECT or rTMS within 6 months before enrollment; 4) previous poor response to ECT; 5) history of psychoactive substance abuse; 6) presence of ECT related contraindications; 7) there are anesthetic risks such as cardiovascular diseases; 8) a history of epilepsy; 9) Those who are not permanent residents of Huizhou or whose address is unknown are not willing to accept follow-up visits.

Design outcomes

Primary

MeasureTime frame
YMRS;

Secondary

MeasureTime frame
Montgomery -Asberg Depression Rating Scale;Positive and Negative Symptom Scales;Stroop Test;Repeatable Battery for the Assessment of Neuropsychological Status,RBANS;

Countries

PR China

Contacts

Public ContactYe Feiying

Huizhou Second People's Hospital

gdhzyfy083@163.com+86 136 6951 2692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026