Painless gastrointestinal endoscopy
Conditions
Interventions
Group 1:Propofol disodium phosphate 6.5mg/kg
Group 2:Propofol disodium phosphate 10mg/kg
Group 3:Propofol disodium phosphate 12.5mg/kg
Group 4:Propofol disodium phosphate 15mg/kg
Group 5:Propofol disodium phosphate 18mg/kg
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients who intend to undergo gastrointestinal endoscopy; (2) 18-65 years old, no gender limit; (3) Body mass index (BMI) 18.5~30kg/m2; (4) The American Association of Anesthesiologists (ASA) graded ?~?. (5) Inspection time within 30min
Exclusion criteria
Exclusion criteria: (1) Patients who refuse to participate in the trial (2) Those with a history of serious heart, brain, lung, liver, kidney and metabolic diseases; (3) Those who have a history of abnormal surgical anesthesia recovery; (4) ECG prompt: heart rate 180mmHg and (or) diastolic blood pressure >110mmHg, or hypotension patients <90/60mmHg; (7) Those with neuromuscular system disease or mental illness; (8) Anemia patients; (9) Suspected of abusing narcotic analgesics or tranquilizers; (10) Those who predict that a difficult airway may or have occurred; (11) Those who are known to have a history of drug allergy, allergic diseases, or allergic constitutions; (12) Those who do not cooperate and cannot communicate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Vital Signs:Blood pressure (BP), heart rate (HR), pulse oxygen saturation (SpO2), respiratory rate (RR);Patient sedation success rate;Intraoperative adverse reactions: body movements, hypotension, hypoxia, respiratory depression, apnoea, choking, abnormal sensations, pruritus, painful injections;Post-operative adverse effects: vertigo, nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's basic information;Time from the start of anaesthesia to the start of the examination;Time for the eyelash reflex to disappear;Surgery time;Wake up time; | — |
Countries
China
Contacts
Public ContactJi Fanceng
Weifang People's Hospital
Outcome results
None listed