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Adjunctive repeated transcranial magnetic stimulation for the cognitive deficits of schizophrenia

Adjunctive repeated transcranial magnetic stimulation for the cognitive deficits in patients with schizophrenia: a clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073220
Enrollment
Unknown
Registered
2023-07-04
Start date
2019-07-01
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia and schizophreniform disorder

Interventions

Sponsors

Shanghai Putuo Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) Diagnosis of schizophrenia and schizophreniform disorder with ICD-10. (2) Aged 18 - 55 years old, Han nationality, right handedness; (3) Course of disorder not less than 1 year; (4) A score of the Wechsler Intelligence Scale > 70; (5) A score of the Positive And Negative Syndrome Scale = 60; (6) Patient's and his/her family members' informed consent.

Exclusion criteria

Exclusion criteria: (1) Contraindication of rTMS or MRI: intracranial hypertension or metal implant(e.g., pacemaker and cochlear prosthesis); (2) Mental retardation, nervous system disease, or severe physical diseases; (3) Traumatic brain injuries; (4) History of alcohol or drug abuse and dependence; (5) Receiving treatment such as MECT that may affect cognitive function due to severe excitement and agitation.

Design outcomes

Primary

MeasureTime frame
cognitive functions;reduction in psychotic symptoms;improvement in other clinical symptoms;rate of adverse event;

Secondary

MeasureTime frame
negative symptoms;improvement in social functions;rate of relapse and re-admission;biochemical indexes;

Countries

China

Contacts

Public ContactHongtao Xie

Shanghai Putuo Mental Health Center

xiehhtt@163.com+86 21 5607 9469

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026