Effect of low-dose folic acid on H-type hypertension patients with different MTHFR C677T genotype

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073217

Enrollment

Unknown

Registered

2023-07-04

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

treatment group: 5 mg of folic acid tablet weekly

Control group:Not use folic acid

Eligibility

Sex/Gender

All

Age

35 Years to 65 Years

Inclusion criteria

Inclusion criteria: Adults who had essential hypertension with total homocysteine concentration greater than 10µmol/L.

Exclusion criteria

Exclusion criteria: The major exclusion criteria were severe renal and hepatic dysfunction, tumor, prescribed treatment with B vitamins or untreated vitamin B deficiency.

Design outcomes

Primary

Measure	Time frame
homocysteine concentrations;	—

Secondary

Measure	Time frame
blood pressure;	—

Countries

China

Contacts

Public ContactHong Mei

The Second Affiliated Hospital of Nanjing Medical University

50329787@qq.com+86 189 5176 2896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026