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A retrospective cohort study on the risk of stroke in relation to residual cholesterol level among people with type 2 diabetes mellitus

A retrospective cohort study on the risk of stroke in relation to residual cholesterol level among people with type 2 diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300073204
Enrollment
Unknown
Registered
2023-07-04
Start date
2023-07-15
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes mellitus

Interventions

Type 2 diabetes+stroke group:none
Type 2 diabetes+non stroke group:none

Sponsors

Zhongda Hospital Affiliated to Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: The information of T2DM patients came from the Zhongda Hospital affiliated to Southeast University, and the follow-up time of the study subjects was from January 1, 2015 to January 1, 2022; At baseline, T2DM cases were collected from the Zhongda Hospital affiliated to Southeast University from January 1, 2015 to January 1, 2017; Age range 18-100 years old; The International Classification of Diseases (ICD) 10th edition (ICD-10) code is E11.0-E11.9. The diagnostic criteria for diabetes were WHO 1999 standards, that is, diabetes symptoms+plasma glucose level at any time = 11.1 mmol/L (200 mg/d L) or fasting plasma glucose (FPG) level = 7.0 mmol/L (126 mg/d L) or oral glucose tolerance test (OGTT) 2 h blood glucose level = 11.1 mmol/L (200 mg/d L).

Exclusion criteria

Exclusion criteria: 1) People who have suffered from ischemic stroke or hemorrhagic stroke before diagnosis of diabetes; 2) Inaccurate or lack of important information such as height, weight, total cholesterol, LDL-C, HDL-C, TG, etc; 3) Have a history of severe liver and kidney dysfunction, malignant tumor, type 1 diabetes, etc; 4) Communication barriers, inability to cooperate with investigators.

Design outcomes

Primary

MeasureTime frame
Remnant cholesterol;total cholesterol;low-density lipoprotein cholesterol;high-density lipoprotein cholesterol;glomerular filtration rate;

Secondary

MeasureTime frame
glycosylated hemoglobin;uric acid;creatinine;C peptide;Fasting blood glucose;apolipoprotein A1;apolipoprotein B;c-reactive protein;fibrinogen;free triiodothyronine;free thyroxine;thyrotropin;

Countries

China

Contacts

Public ContactWencan Ji

Zhongda Hospital Affiliated to Southeast University

17705198296@163.com+86 177 0519 8296

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026