urticaria
Conditions
Interventions
observation group (Take levocetirizine hydrochloride oral solution, once a night, 1.25mg (2.5ml) each time, acute urticaria for 7 consecutive days, chronic urticaria for 28 consecutive days):None
Sponsors
Children's Hospital ZheJiang Univisity School Of Medicine
Eligibility
Sex/Gender
All
Age
0.5 Years to 2 Years
Inclusion criteria
Inclusion criteria: ( 1 ) Age 6 months to 2 years ( including boundary age ), gender unlimited ( 2 ) According to the ' Clinical Pathway Interpretation · Dermatology and Venereal Diseases ( 2022 Edition ) ' diagnostic criteria for urticaria, children with clinically diagnosed urticaria : A ) The rash is a wheal of different size, shape and quantity, which occurs suddenly and subsides rapidly. b ) The existence time of single damage is generally less than 24 hours, and there is no trace after regression. c ) The rash has no fixed predilection site, often accompanied by varying degrees of itching, a few with tingling. d ) The course of disease was different. Acute urticaria was within 6 weeks, and chronic urticaria was more than 6 weeks. ( 3 ) Able to obtain the written consent of the guardian ( 4 ) The guardian can write a diary on behalf of the children.
Exclusion criteria
Exclusion criteria: ( 1 ) Children with allergies to levocetirizine hydrochloride preparations or piperazine derivatives such as hydroxylazine, cetirizine, and cycloazine or children with a history of allergies. ( 2 ) Children with chest tightness or dyspnea, nausea, vomiting, abdominal pain, and diarrhea. ( 3 ) Children who are using a prohibited combination of drugs ( systemic glucocorticoid drugs, omalizumab, cyclosporine and other antihistamine drugs, montelukast, compound glycyrrhizin, systemic antibiotic drugs, and other drugs that are judged by other researchers to affect the determination of test efficacy indicators ). ( 4 ) Children with chronic urticaria who were treated with loratadine and desloratadine within 7 days before the start of the treatment period and other antihistamines within 3 days. Children who had been treated with systemic glucocorticoids, omalizumab, cyclosporine, and compound glycyrrhizin within 30 days. ( 5 ) If breastfed, mothers had children who took antihistamines and glucocorticoids during the trial. ( 6 ) Children with mental illness, immune system disease, blood system disease, systemic infectious disease, and malignant tumor. ( 7 ) Researchers judged that children who were not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse event;UAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life score; | — |
Countries
China
Contacts
Public ContactRen yunqing
Children's Hospital ZheJiang Univisity School Of Medicine
Outcome results
None listed