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Efficacy analysis of transcatheter arterial chemoembolization combined with immunotherapy and targeted therapy in patients at high risk of recurrence after radical surgery for primary liver cancer

Efficacy analysis of transcatheter arterial chemoembolization combined with immunotherapy and targeted therapy in patients at high risk of recurrence after radical surgery for primary liver cancer

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073182
Enrollment
Unknown
Registered
2023-07-04
Start date
2023-07-02
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Sponsors

the first affiliated hospital of Chongqing medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Meeting the diagnostic criteria for primary hepatocellular carcinoma; (2) Clear microvascular invasion by pathological histological examination; (3) Karnofsky functional status score of 70; (4) Child-Pugh grade A-B; (5) Clinical stage I-IIIa; (6) Patients with higher than normal postoperative serological tumor markers; (7) Patients were aware of the study and had signed the consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with co-morbidities of other primary malignancies; (2) Patients with autoimmune diseases; (3) Patients with hematologic disorders; (4) Patients with severe infectious diseases; (5) patients with severe cardiovascular diseases and renal and pulmonary insufficiency (6) Patients with recurrent hepatocellular carcinoma.

Design outcomes

Primary

MeasureTime frame
3-year survival rate;

Secondary

MeasureTime frame
Recurrence rate;Liver and kidney function, blood routine, coagulation function, tumor markers, C-reactive protein;quality of life;complication;

Countries

People's Republic of China

Contacts

Public ContactDu Chengyou

the first affiliated hospital of Chongqing medical university

lanxiangkeyan@163.com+86 139 8370 1066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026