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Clinical Study on the Effects of Induction Dose of Nalbuphine on Pupillary Response

Clinical Study on the Effects of Induction Dose of Nalbuphine on Pupillary Response

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073147
Enrollment
Unknown
Registered
2023-07-03
Start date
2023-07-10
Completion date
Unknown
Last updated
2023-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus

Interventions

sufentanil group:sufentanil 0.3µg/kg
fentanyl group:fentanyl 3µg/kg

Sponsors

the Affiliated Hospital of Yunnan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. 18-60 years old, gender is not limited, 2. American Anesthesiologist Classification (ASA) I-II, 3. Patients who need general anesthesia for elective strabismus surgery, 4.No other eye diseases and normal bilateral pupillary reflexes.

Exclusion criteria

Exclusion criteria: 1.Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past, 2.Having a difficult airway, or being judged to have difficulty in endotracheal intubation (modified Markov score grade III or IV), 3.Patients with a history of systemic disease, 4.Abuse or long-term use of narcotic, sedative, and analgesic drugs.

Design outcomes

Primary

MeasureTime frame
Pupil diameter;

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;Pulse Oxygen Saturation;extubation time;

Countries

China

Contacts

Public ContactSu Guoning

the Affiliated Hospital of Yunnan University

suguoning18@163.com+86 186 8710 7829

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026