Cognitive impairment and addiction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients with American Society of Anesthesiologists Classification grades 1-2 for gastrointestinal endoscopy under general anesthesia in our hospital; 18~65 years old; BMI18.5-24 kg/m²
Exclusion criteria
Exclusion criteria: ( a ) Refusal to sign informed consent form ( b )a known hypersensitivity reaction to any drugs , such as allergy to propofol or benzodiazepines , or intolerance to them ; ( c) a history of cognitive impairment or any neuropsychiatric diseases such as depression, anxiety, Sleep disorder, etc. ( d) language disorders, blurred consciousness, drowsiness, coma, etc ( e) Nicotine, Alcohol dependence and drug addicts ( d )Drinking tea, alcohol, and stimulants in the short term ( f) a recent surgery or major trauma within 14 days prior to the experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| facial expression recognition; interphase decision-making; | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphine -Benzedrine Group score ;Data on intraoperative drug dosage of patients; | — |
Countries
China
Contacts
Peking University Third Hospital