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Effect of goal-directed fluid therapy on extravascular pulmonary water in patients during thoracic surgery: a randomized controlled trial

Effect of goal-directed fluid therapy on extravascular pulmonary water in patients during thoracic surgery: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073115
Enrollment
Unknown
Registered
2023-07-02
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung tumor

Interventions

Group G :Goal-directed fluid therapy
Group C:Traditional fluid therapy

Sponsors

The First Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) thoracoscopic pulmonary resection was performed at selected time; (2) Adult patients between the ages of 18 and 65 years; (3) ASA grade I-III; (4) The duration of the operation is greater than 120 minutes; (5) The patient and his family agree and sign the anesthetic consent; (6) No cognitive dysfunction before operation; (7) Stay in hospital for observation for more than three days after surgery

Exclusion criteria

Exclusion criteria: (1) The patient or family member refuses; (2) Critically ill patients with ASA classification greater than grade III; (3) Patients with COPD and Gold grade 3 or above before surgery; Pneumothorax, large pleural effusion (effusion volume >500ml); (4) Patients with frequent intraoperative arrhythmia, atrial fibrillation, pulmonary hypertension combined with right heart failure, NYHA cardiac function grade 3 or above, congenital heart disease; (5) Patients with severe liver and kidney failure; Patients with peripheral neuropathy, severe anemia (Hb 35kg/m2.

Design outcomes

Primary

MeasureTime frame
Pulmonary ultrasound score of healthy lung during thoracic surgery;

Secondary

MeasureTime frame
The incidence of postoperative pulmonary complications;Cardiovascular adverse events;Incidence of nausea and vomiting;the length of stay;Intraoperative oxygenation parameters;Intraoperative fluid intake;

Countries

China

Contacts

Public ContactYu Fang

The First Affiliated Hospital of Kunming Medical University

fangyu@ydyy.cn+86 138 8809 1314

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026