Prostate cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Men aged 18-75 at the time of signing the informed consent form. 2) Agree to sign the informed consent form. 3) Histologically diagnosed prostate cancer, including prostate adenocarcinoma and other rare pathological types, such as squamous cell carcinoma, ductal adenocarcinoma, intraductal carcinoma, prostatic sarcoma, neuroendocrine carcinoma, small cell carcinoma, etc. 4) Patients must be able to provide blood samples, for patients undergoing radical prostatectomy in research center, they need to provide fresh or archived tumor tissues (formalin-fixed fresh tissues, paraffin-embedded wax blocks) or about 15 (at least 5) freshly cut unstained paraffin sections, the above blood and tissue samples are used for central DNA extraction and HRR gene testing. 5) Eastern Cooperative Oncology Group (ECOG) physical status =1.
Exclusion criteria
Exclusion criteria: 1) Active tuberculosis 2) Severe infection within 2 weeks before enrollment, including but not limited to infection complications leading to hospitalization, bacteremia or severe pneumonia 3) Known human immunodeficiency virus infection 4) Patients with untreated active hepatitis B are not allowed to enter the study 5) Patients with active hepatitis C are not eligible for enrollment 6) Have received HRR gene testing for prostate cancer previously
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease free survival;Distant metastasis free survival; | — |
Countries
China
Contacts
Huashan Hospital, Fudan University