resistant hypertension
Conditions
Interventions
Group 1:laparoscopic sympathetic denervation of bilateral renal artery adventitia
Group 2:laparoscopic sympathetic denervation of unilateral renal artery adventitia
Sponsors
the Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: a. Clinically diagnosed as refractory hypertension; b. Renal artery diameter >=4mm and length >=20mm; c. Age >=18 years old and <=75 years old; d. The patient voluntarily participated in and signed the informed consent, and cooperated with the later follow-up.
Exclusion criteria
Exclusion criteria: a. Renal artery abnormalities: CTA or DSA examination showed mechanical stenosis of either renal artery; Former renal arterioplasty or stent implantation; There were branches in either renal artery and the main artery supplied < 75% of the kidney; Anatomic abnormalities that were evaluated as difficult to insert ablation electrodes; b. Factors of cardiovascular and cerebrovascular instability: myocardial infarction, unstable angina pectoris or cerebrovascular disease occurred within 6 months; c. The patient has other serious organic diseases; d. Patients who participated in other clinical trials within three months prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of blood pressure;Renin/aldosterone; | — |
Countries
China
Contacts
Public ContactBoxin Xue
the Second Affiliated Hospital of Soochow University
Outcome results
None listed