liver cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ?Patients with liver cancer who undergo pathology or abdominal enhancement CT or MRI and meet the definition of primary liver cancer in 2022 Guidelines for the Treatment of Primary Liver Cancer. ?Measurable lesions meeting RECIST criteria. ? Unresectable defined as having four or more lesions with tumor occupying or more than 50% of the liver volume or with significant cirrhotic background, or tumor invasion of major vascular structures, and not amenable to one-stage surgical resection upon evaluation. ?Patients with previously untreated disease. ? liver function Child-Pugh classification grade A/B and Eastern U.S. Collaborative Oncology Group Physical Status Activity (ECOGPS) score <2. ? White blood cell count = 3.0*109/L and no renal, cardiac, cerebral or other significant organ insufficiency disease. ?Informed understanding of various treatment options and good compliance with outpatient follow-up, with complete follow-up data.
Exclusion criteria
Exclusion criteria: ? Patients with combined organic lesions of vital organs such as heart, brain and kidney or with other malignant tumors. ?Patients who have been treated for liver cancer in the past. ? Patients with decompensated liver function or liver function Child-Pugh classification grade C. ?patients with incomplete clinical data. ? Patients with poor medication compliance, pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor progression;Liver and kidney function, blood routine, coagulation function, tumor markers, C-reactive protein; | — |
Countries
People's Republic of China
Contacts
the first affiliated hospital of Chongqing medical university