ovarian cancer
Conditions
Interventions
Control:Without Intervention, feces from healthy person
Observe 1:Without Intervention,feces from ovarian cancer patients with normal platelet at the time of initial diagnosis
Observe 2:Without Intervention,feces from ovarian cancer patients withincreased platelet at the time of initial diagnosis
Sponsors
The Second People's Hospital of Jingdezhen
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Patients diagnosed with epithelial ovarian cancer (serous adenocarcinoma, mucous adenocarcinoma, endometrioid adenocarcinoma, etc.) by biopsy or highly suspected ovarian cancer by imaging, and confirmed with epithelial ovarian cancer by postoperative pathology. ? The patients are generally in good condition, aged 18-75 years old, and have not complicated with serious heart, lung, kidney, liver dysfunction and metabolic diseases. ? For the first time, patients who had not received relevant treatment before and had no serious complications before surgery were collected 10 g of fresh, intermediate-posterior, and internal stool samples and quickly stored at -80?. Fecal DNA extraction and 16S rRNA gene sequencing were performed to detect intestinal flora. ?No antibiotics or other drugs were used in the 3 months prior to enrollment.
Exclusion criteria
Exclusion criteria: ? Have hemophilia or abnormal diseases related to the blood system. ? Other immune diseases that cause PLT abnormalities. ? With other cancers. ? Other chronic diseases. Another 30 healthy people in the same period were taken as controls.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal flora;platelet; | — |
Countries
China
Contacts
Public ContactXiaohui Wang
Jingdezhen Second People's Hospital
Outcome results
None listed