Ischemic stroke in patients with respiratory tract flora characteristics research

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300073071

Enrollment

Unknown

Registered

2023-06-30

Start date

2023-07-01

Completion date

Unknown

Last updated

2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Healthy group:N/A

First-ever acute ischemic stroke group:N/A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with first-ever acute ischemic stroke and healthy physical examination population during 2023-6 to 2025-6; 2.18 years < age < 80 years; 3. No gender limitation; 4. Complete clinical data and complete follow-up data; 5. Non-pregnant; 6. No antitumor drugs, glucocorticoids or other immunosuppressants have been used in the past 1 month; 7. No active infection within 2 weeks prior to admission; 8. Voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Stroke onset > 7 days; 2. Can not cooperate to induce sputum; 3. Antibiotics, prebiotics or probiotics used in the three months prior to admission; 4. Symptoms of gastrointestinal disease within the past three months; 5. Hospital admission 48 hours after the onset of acute ischemic stroke; 6. Active infection within 2 weeks prior to admission; 7. Failure to provide stool samples and sputum samples within 48 hours after admission.

Design outcomes

Primary

Measure	Time frame
Flora;	—

Secondary

Measure	Time frame
Serum metabolite;Serum inflammatory factor;	—

Countries

China

Contacts

Public ContactZhang Lei

The Fifth Affiliated Hospital of Sun Yat-sen University

zhangl92@sysu.edu.cn+86 137 2620 9240

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026