Myopia
Conditions
Interventions
Experimental group A:Wearing aspherical base curve orthokeratology with 3 D defocus
Experimental group B:Wearing aspherical base curve orthokeratology with 4.5 D defocus
Experimental group C:Wearing aspherical base curve orthokeratology with 6 D defocus
Control group:Wearing spherical base curve orthokeratology
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
8 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 8-12 years old; 2.Visual acuity: Monocular 1.0 or better; 3. Refractive errors: manifest ocular refraction in either eye; Spherical refraction >= -4.00D and <= -0.75D; 4. Astigmatism <= 1.50DC for axis 180±30; 5. Anisometropia <= 1.0D, 6. Available for scheduled and unscheduled visits at the West China Hospital for 12 months after treatment commences; 7. Sleep at least eight hours per night
Exclusion criteria
Exclusion criteria: 1. Shallow anterior chamber or intraocular pressure > 21mmHg; 2. Suffering from keratitis, keratoconus, glaucoma, strabismus, amblyopia, and other eye diseases; 3. Suffering from mental illness; 4. Serious systemic history, such as cardiopulmonary insufficiency; 5. Participate in other clinical trials 30 days before screening 6. Have used any products that delay the progression of myopia, such as specially designed lenses such as orthokeratology lenses, multi-focal contact lenses, peripheral defocusing lenses, atropine drugs, red light therapy devices, etc.; 7. Poor compliance, researchers believe that it is not appropriate to continue to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective and objective refraction;Visual acuity;Wavefront aberration;Corneal topography;Axial length;Contrast sensitivity;multispectral refraction topography;Optical coherence tomography;Visual quality questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal endothelial cell; | — |
Countries
China
Contacts
Public ContactLiu Longqian
West China Hospital, Sichuan University
Outcome results
None listed