colon cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 45-70 years old ASA Level I - II Body mass index 18.5 = BMI<28 Planned postoperative intravenous patient-controlled analgesia for 48 hours Able to use postoperative intravenous analgesia pump correctly
Exclusion criteria
Exclusion criteria: Preoperative history of liver and kidney diseases History of psychiatric disorders and chronic pain Long term history of analgesic drug use Individuals who cannot cooperate in evaluating pain Recently taken drugs that inhibit or induce liver CYP3A4 enzyme activity (1 week before) or food (3 days before) Patients receiving neoadjuvant chemotherapy before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative VAS scores;postoperative fentanyl dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative Ramsay scores;degree of ponv; | — |
Countries
China
Contacts
Department of Anesthesiology,Zhongshan Hospital Affiliated to Fudan University