Upper abdominal disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) American Society of Anesthesiologists (ASA) Physical Status classification: I-III 2) Patients aged 18-75 years 3) Median upper abdominal incision with an estimated operation time of 3h±0.5h 4) Participants provided written informed consent 5) Scheduled for upper abdominal surgery
Exclusion criteria
Exclusion criteria: 1) Opioid abuse 2) Chronic pain and using analgesics before surgery 3) The therapy of corticosteroids before surgery 4) Motion sickness 5) Cognitive disorder 6) Contraindications for erector spinal block, paravertebral block (history of severe coagulopathy, infection, or allergy to local anesthetic) 7) 18.5=BMI=30kg/m2 8) Organic heart disease and severe arrhythmia 9) Hepatic, renal disorders 10) Palliative surgery, emergent surgery or reoperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative sufentanil equivalents during the surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| perioperative consumption of sufentanil ;NRS scores at 3, 6 12 and 24 h after surgery;the quality of recovery-15 score at 24 and 48h;relevant complications of nerve block such as infection, local hematoma, and pneumothorax; ; | — |
Countries
China
Contacts
Shanghai Changhai Hospital