emergence agitation
Conditions
Interventions
group R:remimazolam total intravenous general anesthesia
group P:propofol total intravenous general anesthesia
group S:sevoflurane inhalation anesthesia
Sponsors
Affiliated Boai Hospital of Zhongshan, Southern Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1.1 to 7 years; 2. Body weight ranged from 4 to 25 kg; 3.ASA(American society of anesthesiologists)?~?; 4. Mallampati grade?~?.
Exclusion criteria
Exclusion criteria: 1. Those who have a history of a recent upper respiratory infection; 2. Those who are allergic to drugs; 3. Obvious cardiopulmonary dysfunction; 4. Those who have a history of neurological and psychiatric disorders; 5. Sedative or analgesic drugs were used within 24 hours before surgery; 6. Those who have a family history of malignant hyperthermia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total incidence of emergence agitation in children;Incidence of severe emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of surgery ;duration of anesthesia;extubation time;MAP and heart rate at admission, tracheal intubation, Trocar puncture, and extubation;Incidence of injection pain during induction of anesthesia;MOAA/S score for immediate sedation after tracheal extubation;The FLACC pain score were recorded at the time of discharge from PACU;The agitation-sedation RASS score were recorded at the time of discharge from PACU;The delirium PAED score were recorded at the time of discharge from PACU;FLACC pain score at 24 hours after surgery;Incidence of adverse events: laryngspasm, tongue suffix, bucking, hypoxemia, PONV, abdominal distention; | — |
Countries
China
Contacts
Public ContactZeng Wei
Department of Anesthesiology.Affiliated Boai Hospital of Zhongshan, Southern Medical University
Outcome results
None listed