Functional dyspepsia
Conditions
Interventions
Group 1:Esomeprazole 20mg once a day, Medilac-s 0.5g three times a day. Patients were treated for 28 days.
Group 2:Esomeprazole 20mg once a day, placebo 0.5g three times a day. Patients were treated for 28 days.
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years; 2. Diagnosed as functional dyspepsia according to the Rome IV standard; 3. Volunteer to participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Positive Hp infection was confirmed by 13C urea breath test, rapid urease test, etc.; 2. Using probiotics, prokinetic drugs, immunosuppressive drugs, or antibiotics within the past month; 3. Severe heart, lung, liver, and kidney diseases; 4. Diabetes and malignant tumor; 5. Previous history of abdominal surgery; 6. Pregnant and lactating women; 7. In addition to the above, researchers have determined that patients are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 7-point Global Overall Symptom Scale score at 4 weeks of treatment;Fecal microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short chain fatty acids in feces;Neurotransmitter in blood;7-point Global Overall Symptom Scale score at 1 week, 2 weeks, and 3 weeks of treatment;Functional digestive disease quality of life questionnaire at 4 weeks of treatment;Side effects; | — |
Countries
China
Contacts
Public ContactXu Shu
The First Affiliated Hospital of Nanchang University
Outcome results
None listed