Cardiogenic cardiac arrest
Conditions
Interventions
Trial group:ECPR conventional treatment combined with HA380 hemoperfusion
Control group:ECPR conventional treatment
Sponsors
Emergency Department, Nanjing Medical University First Affiliated Hospital and Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ?=18 years old; ? not pregnant; ?ECMO support time exceeds 72 hours; ? Cardiogenic cardiac arrest; ? did not participate in other clinical trials; ? Guardian signs informed consent.
Exclusion criteria
Exclusion criteria: ? Trauma; ? No written informed consent ; ? Patients with uncontrolled bleeding; ? Patients with severe leukopenia (< 0.5×109/L) or severe thrombocytopenia (< 30×109/L); ? Patients who are allergic to hemoperfusion and filter; ? Use of ECMO as a transition to heart transplantation; ?Any other conditions deemed inappropriate by the investigator for participation in this study, such as the terminal state of a chronic disease, and those with no likelihood of survival or discharge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of VA-ECMO; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory factor levels;Blood product infusion volume;Hemodynamic parameters;Duration of mechanical ventilation;Length of stay;All-cause mortality; | — |
Countries
China
Contacts
Public ContactXufeng Chen
Emergency Department, Nanjing Medical University First Affiliated Hospital and Jiangsu Province Hospital
Outcome results
None listed