Comparison of curative effect and safety between vascular interventional and endoscopic therapy on the prevention of EGVB in patients with PVT/CTPV

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300073012

Enrollment

Unknown

Registered

2023-06-29

Start date

2023-06-30

Completion date

Unknown

Last updated

2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

portal vein thrombosis/Cavernous Transformation of the Portal Vein

Interventions

Control group:endoscopic sequential therapy

Interventional surgery group:Vascular interventional therapy

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age 18 to 75 years; 2.Diagnosed CTPV/PVT patients according to clinical manifestations, laboratory and imaging examinations, who suffered from EGVB previously.

Exclusion criteria

Exclusion criteria: 1.Previous TIPS, portal vein plasty or surgical shunt; 2.Complicated with other portal hypertension related complications, including refractory ascites, hepatorenal syndrome and hepatopulmonary syndrome. 3.Patients with Child-Pugh score over 12. 4.Uncontrolled EGVB or stabilized for less than 2 weeks; 5.Complicated with infection before surgery. 6.Dysfunction of organs including heart, lung, kidney(CrCl<30ml/min) and brain; 7.Liver cancer and other malignant tumors beyond Milan criteria; 8.Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Esophagogastric variceal bleeding;	—

Secondary

Measure	Time frame
cirrhosis related events;	—

Countries

China

Contacts

Public ContactHao Wu

Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University

594264513@qq.com+86 189 8060 1287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026