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The impact of using Kuanxiong Qiwu Ji after emergency PCI for acute myocardial infarction on ventricular remodeling and cardiopulmonary function: a randomized, controlled, double-blind clinical trial.

Effect of Kuanxiong Qiwu Ji on ventricular remodeling and cardiopulmonary function in patients with acute myocardial infarction undergoing emergency PCI

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300073000
Enrollment
Unknown
Registered
2023-06-29
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myocardial infraction

Interventions

experimental group:The experimental group received additional use of Kuanxiong Qiwu Ji (produced by Subo Pharmaceutical Industries Ltd.), 2 puffs under the tongue, 3 times a day for a duration of 3 mo
control group:Control group patients received routine medication after PCI procedure and addition of placebo (produced by Subo Pharmaceutical Industries Ltd.), 2 puffs under the tongue, 3 times a day

Sponsors

Tai'an Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age > 18 years; 2. Underwent emergency PCI treatment; 3. Patients have normal cognition; 4. No use of Kuanxiong Qiwu Ji before surgery; 5. Patients agree to the study plan and sign relevant informed consent form

Exclusion criteria

Exclusion criteria: (1) Allergy to Kuanxiong Qiwu Ji ; (2) Patients with cardiogenic shock; (3) Severe liver or kidney dysfunction; (4) Patients who have used Kuanxiong Qiwu Ji before surgery; (5) Patients with contraindications for the use of Kuanxiong Qiwu Ji ; (6) Patients with poor compliance or unable to complete the treatment as required.

Design outcomes

Primary

MeasureTime frame
Left ventricular end diastolic dimension;Left ventricular end-diastolic volume;Left ventricular end-systolic volume;Left Ventricular Ejection Fractions;left ventricular reconstruction index;

Secondary

MeasureTime frame
peak O2;The partial pressure of CO2 in tidal volume during rest and exercise;Anaerobic Threshold;VO2/HR;VE/Vco2;Metabolic equivalents;Heart Rate;Cardiac Index;Cardiac Output;Stroke Volume;Mean Artery Pressure;PaO2/FiO2;

Countries

China

Contacts

Public ContactZhong Xu

Tai'an Central Hospital

doctor_2023@163.com+86 138 0538 3288

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026