knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of Chinese and Western medicine for knee osteoarthritis; (2) Age =38 years old and =70 years old, gender unlimited; (3) Volunteer to participate in the study and sign the informed consent; (4)KL is graded as Class I or II.
Exclusion criteria
Exclusion criteria: (1) Knee trauma and surgical history; (2) Patients with tumors, tuberculosis, osteomyelitis and other diseases in the knee; (3) Psoriasis, syphilitic neuropathy, brown yellow disease, metabolic bone disease, acute trauma, etc.; (4) Severe liver and kidney insufficiency, severe cardiovascular disease, diabetes and mental disease; (5) Patients with metal implants or claustrophobia and other MRI contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee MRI;IL-1ß;IL-6;TNF-a; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine