Periodontitis
Conditions
Interventions
regenerative group:autologous platelet concentrates + bone graft + guided tissue regeneration
resective group:osseous resective surgery
Sponsors
Department of Periodontics, Peking University School and Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1: 18-65 years old, systemically healthy 2: diagnosed with periodontitis, and have completed periodontal initial therapy for more than 3 months, with good oral hygiene 3: sites with residual probing depth = 5mm and bleeding on probing, x-ray shows the depth of infrabony defects = 3 mm (including osseous craters) 4: normal pulp vitality or has received complete root canal treatment 5: normal preoperative laboratory testing, no surgical contraindications
Exclusion criteria
Exclusion criteria: 1: Teeth with grade III mobility, hopeless prognosis, or the defects associated with furcation involvement 2: women who plan to become pregnant in the short term, pregnant or lactating women 3: smokers 4: receiving orthodontic treatment 5: patients with uncontrolled diabetes or other systemic diseases that affect tissue healing 6: patients who are allergic to grafting materials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical attachment level; | — |
Secondary
| Measure | Time frame |
|---|---|
| gingival recession;probing depth;bone sounding;bleeding index;plaque index;BD-BC;BD-CEJ;radiographic depth of defect;radiographic angle of defect;volume of defect;early wound healing index; | — |
Countries
China
Contacts
Public ContactXiangying Ouyang
Peking University School and Hospital of Stomatology
Outcome results
None listed