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Effect of continuous intravenous infusion of lidocaine on postoperative delirium in elderly patients undergoing hip fracture surgery

Effect of continuous intravenous infusion of lidocaine on postoperative delirium in elderly patients undergoing hip fracture surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072987
Enrollment
Unknown
Registered
2023-06-29
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hip fracture

Interventions

group L:Before anesthesia induction, lidocaine group was given lidocaine 1 mg / kg (0.15 ml/ kg), the infusion time was 10 minutes, and 1% lidocaine was continuously infused with a micropump for 0.15
group C:Given by normal saline bolus and infusion, its volume and rate changes were the same as those of lidocaine group

Sponsors

Lishui People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Aged 65-90 years, BMI 18.5-27.9 kg/m2; 2. ASA class I-II. 3. It is planned to perform hip arthroplasty or intertrochanteric closed reduction and intramedullary nail fixation under general anesthesia. 4. The patients and their families knew the purpose of this study and voluntarily signed a written informed consent.

Exclusion criteria

Exclusion criteria: ? Patients with neurological or psychiatric diseases or communication disorders before operation; ? Preoperative MMSE score < 23; ? Plan to send patients to the intensive care unit after operation; ? Patients with severe arrhythmia, such as sick sinus syndrome, second and third degree atrioventricular block or significant sinus bradycardia (HR < 50 beats / min); ? Patients with liver and kidney dysfunction; ? Previous history of local anesthetic allergy or local anesthetic poisoning.

Design outcomes

Primary

MeasureTime frame
postoperative delirium;

Secondary

MeasureTime frame
Postoperative delirium onset time;Duration of postoperative delirium;Postoperative delirium severity;emergence agitation;Patient satisfaction with pain management;Adverse reactions (hypotension, hypertension, bradycardia, tachycardia, local anesthetic toxicity);

Countries

China

Contacts

Public ContactDuan Gongchen

Lishui People's Hospital

981225178@qq.com+86 189 5709 3030

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026