Study on anesthesia effect of obese patients
Conditions
Interventions
R1:After entering the operating room, the invasive arterial blood pressure, heart rate, electrocardiogram, pulse oxygen saturation and bifrequency index of brain (BIS) were continuously monitored. Int
R2:The dose of remazolam in R2 group was calculated according to ideal body weight (IBW), and the other interventions were the same as those in R1 group.
R3:The dose of remazolam in the R3 group was calculated by fat free body weight (LBW), and the other interventions were the same as those in the R1 group.
Sponsors
The First Affiliated Hospital of the University of South China
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing endotracheal intubation under elective general anesthesia; (2) ASA grade ? ~ ?; (3) Patients aged 18-60 years old; (4) Body mass index 28kg/m2 or above; (5) The patient understands the clinical trial and signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) History of allergy to narcotic drugs; (2) mental and nervous system diseases; (3) Serious heart, lung, kidney and metabolic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure and heart rate;The occurrence of relevant adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Administration onset time;Additional administration times;postoperative agitation; | — |
Countries
China
Contacts
Public ContactTang Hui
The First Affiliated Hospital of the University of South China
Outcome results
None listed