Pulmonary, mediastinal or chest wall surgery
Conditions
Interventions
M group:Magnesium sulfate (20 mg/kg) was diluted with normal saline to 30 mL and rinsed for 1 minutes 15 minutes before anesthesia induction. DLT was immersed in sterile normal saline at (24 ± 1) degr
T group:Normal saline 30 mL was given 15 minutes before induction of anesthesia for 1 minutes. DLT was immersed in sterile normal saline at (40 ± 1) degrees Celsius for 10 minutes before tracheal intu
SN group:Normal saline 30 mL was given 15 minutes before induction of anesthesia for 1 minutes , and DLT was immersed in sterile saline at (24 ± 1) degrees Celsius for 10 minutes before tracheal intub
MT group:Magnesium sulfate (20 mg/kg) was diluted with normal saline to 30 mL and rinsed for 1 minutes 15 minutes before anesthesia induction. DLT was immersed in (40 ± 1) degrees Celsius sterile norm
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective thoracic surgery with double-lumen endobronchial intubation under general anesthesia and undergoing pulmonary, mediastinal or chest wall surgery; 2. Aged >= 18 years; 3. American Society of Anesthesiologists (ASA) I-III.
Exclusion criteria
Exclusion criteria: 1. Preexisting sore throat and hoarseness; 2. The history of upper respiratory tract infection in the past 1 week; 3. Patients with known intubation difficulties, including mouth opening less than 3.5 cm, Mallampati grade 3-4, head backward limitation; 4. Steroids and non-steroidal anti-inflammatory drugs were used within 3 days before surgery; 5. Allergic to magnesium sulfate; 6. The nasogastric tube was inserted 24 hours before operation or within 24 hours after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sore throat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of sore throat;Severity of sore throat;The incidence and severity of hoarseness;The 15-item quality of recovery scale ( QoR-15 ) scores;Length of postoperative hospital stay;Incidence of pulmonary complications;patient satisfaction; | — |
Countries
China
Contacts
Public ContactLiu Jindong
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed