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Effects of dietary carbohydrate on T cell subsets and intestinal microecology in rural patients with hypertension

Effect of dietary carbohydrate on T cell subsets and intestinal microecology in rural patients with hypertension and its mechanism

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072978
Enrollment
Unknown
Registered
2023-06-29
Start date
2023-06-30
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Control group:The refined rice noodles are issued according to the standard of 300g per person per day
Intervention group:Whole grain staple food is distributed at a standard of 300g per person per day

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Previous hypertension group inclusion criteria: hypertensive patients who had participated in the 2021 study of "The effect of dietary quality Index on T cell subsets of rural hypertensive patients and its mechanism"; (2) Inclusion criteria for the newly diagnosed hypertension group: Participants who had participated in the "Study on the Influence of Dietary Quality Index on T cell subsets of Rural hypertensive Patients and its Mechanism" in 2021 and were classified as non-hypertensive patients, those with newly diagnosed hypertension from 2021 to 2023 were enrolled in the hypertension follow-up registration at Zhangfang Community Hospital and included in chronic disease management; (3) Previous non-hypertensive group inclusion criteria: Participated in the "Study on the Influence of Dietary Quality Index on T cell subsets of rural hypertensive Patients and its mechanism" in 2021, and were enrolled as non-hypertensive patients. So far, no non-hypertensive patients have been diagnosed with hypertension; (4) The inclusion criteria of the non-hypertensive group were supplemented: there was no clear diagnosis of hypertension and no participation in the 2021 study on the effect of dietary quality Index on T cell subsets of rural hypertensive patients and its mechanism, and non-hypertensive patients matched with newly diagnosed hypertensive patients according to gender and age. (5) Did not participate in the 2021 study on the effect of Dietary quality Index on T cell subsets of rural hypertensive patients and its mechanism, and met the requirements of hypertensive/non-hypertensive patients matched by gender, age and the 2021 survey lost access population.

Exclusion criteria

Exclusion criteria: (1) Patients with rheumatism, SLE and other immune diseases; (2) mental abnormality can not cooperate; (3) Severe liver and kidney diseases may lead to immune abnormalities; (4) physical disability can not cooperate with body measurement, body composition detection; (5) refuse to draw blood, stool sampling.

Design outcomes

Primary

MeasureTime frame
systolic pressure;diastolic blood pressure;body composition;

Secondary

MeasureTime frame
c reactive protein;t cell subset;IL-22;

Countries

China

Contacts

Public ContactHong zhongxin

Beijing Friendship Hospital, Capital Medical University

lichengyys@126.com+86 188 1169 5832

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026