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To explore the effects of early enteral nutrition guided by phase Angle combined with indirect calorimetry on nutritional status and prognosis of critically ill patients

To explore the effects of early enteral nutrition guided by phase Angle combined with indirect calorimetry on nutritional status and prognosis of critically ill patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300072974
Enrollment
Unknown
Registered
2023-06-29
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional status of critically ill patients

Interventions

Low-phase Angle conventional caloric feeding group:Deliver 90% of the caloric target
Low-phase Angle low-calorie feeding group:Deliver 60% of the calorie target
High-phase Angle conventional caloric feeding group:Deliver 90% of the calorie target
High-phase Angle low-calorie feeding group:Deliver 60% of the calorie target

Sponsors

Subei People's Hospital of Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Over 18 years old. (2) Enteral nutrition support was expected within 24-48 hours after admission to ICU. (3) Expected duration of nasogastric enteral nutrition =7 days.

Exclusion criteria

Exclusion criteria: (1) Delayed enteral feeding: uncontrollable shock (norepinephrine >0.4µg/kg/min), active upper gastrointestinal bleeding, intestinal ischemia, intestinal obstruction, abdominal compartment syndrome after active resuscitation. (2) Unable to perform phase Angle measurement: patients with pacemaker or implantable defibrillator, amputees or limb prostheses, and impaired skin integrity at the measurement site. (3) Unable to perform indirect calorimetry measurement: pneumothorax, bronchial fistula, and chest drainage. (4) Others: end-stage patients, DNR, brain death, pregnancy, liver transplantation, burns.

Design outcomes

Primary

MeasureTime frame
phase angle;NUTRIC score;albumin;prealbumin;total protein;hemoglobin;Total lymphocyte count;urea nitrogen;

Secondary

MeasureTime frame
white blood cell;c-reactive protein;procalcitonin;ICU Mortality;In-hospital mortality;28-day mortality;Infection rate during ICU stay;Days of mechanical ventilation;length of ICU stay;

Countries

China

Contacts

Public ContactLin Hua

Subei People's Hospital of Jiangsu Province

LH1391213@163.com+86 180 5106 0558

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026