Chronic Renal Failure
Conditions
Interventions
Non-dialysis patients diagnosed with stage 5 CKD.:Not applicable.
Sponsors
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ?Patients aged 18 to 75 years regardless of genders (according to the date of obtaining informed consent). ?Diagnosis of stage 5 CKD before trial. ?No involvement of any dialysis treatments, namely peritoneal dialysis, hemodialysis, as well as continuous renal replacement therapy (CRRT), prior to the study. ?Able to give informed consent and comply with the study protocol voluntarily.
Exclusion criteria
Exclusion criteria: ?Patients with malignant tumors and severe primary diseases, likely cardiovascular, cerebral, hepatic, or hematopoietic system diseases. ?Any medical conditions which put the non-dialysis participants at increased risk ;e.g., the presence of poorly controlled volume overload, hyperkalemia, acidosis, or uremic encephalopathy etc. ?Ongoing antibiotics therapy or suffering from serve infections before trial. ?Unable to comprehend and follow study procedures and instructions. ?Patient’s condition is considered as inappropriate by assigned doctor or investigator. ?Participating in another clinical trial(s) currently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Syndromes of TCM.;Quantitative of serum IS.;Fecal microbiota.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index (BMI);The average daily consumption of protein.;Serum creatinine (SCr).;Blood urea nitrogen (BUN).;Clinical endpoints (including undergoing dialysis, kidney transplantation or death).; | — |
Countries
People's Republic of China
Contacts
Public ContactYongsheng Wang
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine)
Outcome results
None listed